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Islets of Langerhans ( Pancreas )

Islets of Langerhans .  What does mean Islets of langerhans? Endocrine cells of pancreas form groups of cells called Islets of Langerhans. There are four kinds of cells in islets of Langerhans which secrete hormones.  (1) Alpha (x) cells: They are 20% and secrete glucagon. Glucagon is a hyperglycemic hormone. It stimulates the liver for glucogenolysis and increases the blood glucose level.   (2) Beta (B) cells: They are 70% and secrete insulin. Insulin is a hypoglycemic hormone. It stimulates liver and muscles for glycogenesis. This lowers blood glucose level.   3) Delta (8) cells: They are 5% and secrete somatostatin. Somatostatin inhibits the secretion of glucagon and insulin. It also decreases the gastric secretions, motility and absorption in the digestive tract. In general it is a growth inhibiting factor.   (4) PP cells or F cells: They form 5%. They secrete pancreatic polypeptide (PP) which inhibits the release of pancreatic juice...